Metabolism describes all the chemical processes inside your body to keep you alive and your organs functioning normally, such as breathing, repairing cells, and digesting food. Body size and fat/muscle balance, age, gender, and genes all play a role in the speed of your metabolism. In addition, your levels of specific hormones can affect your metabolism, particularly cortisol, testosterone, and thyroid stimulating hormone (TSH).
Who Should Consider This Test?
This test is an ideal option for anyone who suspects they have an irregular metabolism. Disrupted metabolism can affect body weight, cause skin issues, lead to mood changes, alter appetite, and decrease energy levels.
Any abnormalities in the three hormones tested may require additional testing to identify the cause.
Signs of unbalanced metabolism can include:
Irregular heart rate
Body weight changes
Signs of unbalanced metabolism:
Body weight changes
Irregular heart rate
What’s Included in the Metabolism Test?
Cortisol is a steroid hormone that is predominantly produced in the adrenal gland. It is widely known as the body’s stress hormone, as it is released in response to low blood sugar and stress. Cortisol can influence nearly every organ system. It helps to increase blood sugar, is involved in the metabolism of fat, protein, and carbohydrates, suppresses the immune system and inflammatory response, helps control blood pressure, is involved in memory formation, aids in the sleep-wake cycle, and decreases bone formation.
Blood concentrations of cortisol differ during the day, with higher levels typically occurring in the morning. Reference ranges provided by the Endocrine Society are 5-25 μg/dL at 8am and 2-14 μg/dL at 4pm.
Testosterone is the primary sex hormone in males, but it is also important in females. It plays a role in libido, muscle and fat distribution, bone growth, red blood cell production, and energy levels. Most testosterone in circulation is transported by proteins, and only the remaining small fraction of testosterone is circulating in the biologically active free form. Free testosterone is what is measured in this Metabolism Test.
The normal free testosterone range in adult males is 245 – 785 pmol/L. It is considerably lower in females at just 3 – 65 pmol/L.
Thyroid stimulating hormone (TSH)
Thyroid stimulating hormone (TSH) is a hormone produced in the pituitary gland that signals the production of the thyroid hormones – thyroxine (T4) and triiodothyronine (T3) from the thyroid gland. These hormones help regulate many different processes around the body, playing a major role in the metabolism, growth, and development of the human body.
Healthy adults typically have TSH levels within a reference range of 0.3-4.5 mIU/L. Abnormal TSH levels can indicate tumors of the pituitary, thyroid hormone resistance, hypothyroidism, or hyperthyroidism.
How It Works
Step 1. Order your test.
Choose the test that matches your need from our large array of tests. The kit will be delivered to your doorstep. There is no need to leave the comfort of your home.
Step 2. Collect your sample.
Collect your sample using the included instructions. Return your sample using the prepaid, pre-addressed packaging provided.
Step 3. Access your results online
Your sample will be tested as soon as it arrives at our lab. Access your results securely online using your via Therizon Connect.
Use TherizonConnect to view your Test Results Quickly and Easily
The results are only available through therizon, a free, secure patient portal that you can access on your smartphone, tablet, or desktop. You can also share your results with your doctor, family, or friends.
Details and FAQs
Here are the answers to the most frequently asked questions about our Metabolism Test. Please feel free to contact us if you have any other questions.
How does the Metabolism Test work?
Self-collect your sample following the detailed instructions included in the kit. Place your sample in the specimen bag provided and mail it back to the lab using the prepaid envelope inside the kit.
Our lab uses verified and approved chemiluminescent microparticle immunoassays (CMIAs) to accurately measure your cortisol, testosterone and TSH levels. Your results are available through our online portal as soon as testing is complete.
Will I receive any guidance with my results?
All result reports will include brief and easy to understand interpretations of each of the biomarkers tested. Background information is also available, but we recommend that you share your test results with your healthcare provider to obtain the most benefit from your test results.
Are there medical professionals involved in the process?
All of our tests are developed with advice and input from medical professionals.
What is the link between cortisol and metabolic syndrome?
Metabolic syndrome (MetS) refers to a range of metabolic derangements, including insulin resistance, hypertension, high glucose and triglycerides, low HDL-cholesterol, and abdominal obesity. MetS increases the risk of type 2 diabetes and cardiovascular disease. Although the primary mechanism of MetS is insulin resistance, research also suggests that slightly elevated cortisol is another contributing factor towards the development of MetS.
How can I control my cortisol levels?
Cortisol levels increase in response to stress; hence reducing your stress also helps to lower cortisol levels. Proven ways to reduce stress and cortisol levels include yoga, listening to relaxing music, meditation, maintaining healthy relationships. Other ways to reduce cortisol levels include getting adequate sleep and exercise, eating healthy foods (particularly reduced sugar intake), and having fun.
What are my options if I have abnormal results?
It is important to share any abnormal results with you healthcare provider, as they can take into consideration your medical history, any previous test results, physical examinations, and other factors to determine the best treatment option.
What can cause thyroid hormone changes?
Thyroid hormone levels may fluctuate due to stress, diet, medications, childbirth, and menopause.
Hypothyroidism can be caused by Hashimoto’s thyroiditis (autoimmune condition), postpartum thyroiditis (temporarily affects 5-9% of women after childbirth), iodine deficiency, or a non-functioning thyroid gland (from birth).
Hyperthyroidism can be caused by Graves’ disease (autoimmune condition), overactive nodules within the thyroid, or excessive iodine.